Charcot-Marie-Tooth disease: extensive cranial nerve involvement on CT and MR imaging.

نویسندگان

  • Todd R Aho
  • Robert C Wallace
  • Alan M Pitt
  • Kumaraswamy Sivakumar
چکیده

We report a case of genetically verified Charcot-Marie-Tooth disease in which the patient had cranial nerve symptoms. CT and MR imaging demonstrated enlargement of several cranial nerves, as well as their skull-base foramina, with faint contrast material enhancement identified.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Imaging findings of Lower Extremity Peripheral Nerves in Charcot-Marie Tooth

Objective: Charcot-Marie Tooth (CMT) disease is the most common inherited neurological disorder of lower motor neurons, and manifests with lower extremity weakness and sensory defects. Musculoskeletal imaging findings in CMT include cavovarus foot alignment and peripheral muscle atrophy. There is a lack of literature describing the imaging appearance of peripheral nerves in patients with CMT. T...

متن کامل

Charcot–Marie–Tooth disease: Genetics, epidemiology and complications

Background and aims: Charcot Marie Tooth disease (CMT) is the most prevalent hereditary neuropathy and its frequency is 1 in 2500. CMT is a heterogeneous disease and has different clinical symptoms. The prevalence of CMT and involved genes differ in different countries. CMT patients experience considerable sleep problems and a higher risk of decreased quality of life. In this w...

متن کامل

Hypertrophic cranial pachymeningitis: assessment with CT and MR imaging.

Three patients with diffuse idiopathic cranial pachymeningitis with predominant involvement of the tentorium and falx are reported. Progressively increasing headaches were the usual symptoms, along with ataxia and various cranial nerve palsies. CT in all cases and MR imaging in two cases detected isolated thickened dura mater. In one case, MR depicted dural involvement as a very large, hypointe...

متن کامل

A novel Gypsy founder mutation, p.Arg1109X in the CMT4C gene, causes variable peripheral neuropathy phenotypes.

BACKGROUND Linkage, haplotype and sequencing analysis in a large Spanish Gypsy kindred with multiple members affected by autosomal recessive peripheral neuropathy led to the identification of a novel mutation, p.Arg1109X, in the CMT4C gene. The screening of further unrelated patients, and of a panel of ethnically matched controls, showed that p.Arg1109X is an ancestral mutation which occurs in ...

متن کامل

MR imaging of the cauda equina in hereditary motor sensory neuropathies: correlations with sural nerve biopsy.

BACKGROUND AND PURPOSE Although spinal root abnormalities are known to occur, spinal MR examination is seldom performed in hereditary motor and sensory neuropathies (HMSN). The following work was undertaken to assess the MR imaging spectrum of lumbosacral spinal nerve root abnormalities and determine whether intradural nerve root involvement could be related to any biopsy feature. METHODS Ten...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • AJNR. American journal of neuroradiology

دوره 25 3  شماره 

صفحات  -

تاریخ انتشار 2004